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 Photo: WHO/STB
 55th Session of the WHO Regional
 Committee for Africa at the "Joaquim
 Chisano" center in Maputo,
 Mozambique.
[ Communiqué ]An update of information from the Stop TB Partnership and our Partners

Issue No.42, September 2005

NEWS FROM THE STOP TB PARTNERSHIP SECRETARIAT

For a selection of weekly TB news articles, visit our news page

STOP TB PARTNERSHIP

  • WHO DECLARES TB AN EMERGENCY IN AFRICA
    On 25 August in Maputo, the World Health Organization (WHO) Regional Committee for Africa comprising 46 ministers of health declared tuberculosis an emergency in the African region, a response to an epidemic that has more than quadrupled the annual number of new TB cases in most African countries since 1990 and is continuing to rise across the continent, killing more than half a million people every year.

    The address to the Committee by the Stop TB Delegation was presented by Dr Luis Gomes Sambo, WHO Regional Director for Africa. The Stop TB delegation included Dr Jaap Broekmans, Director, KNCV; Ms Lucy Chesire, Kenyan TB/HIV activist; Dr Marcos Espinal, Executive Secretary, Stop TB Partnership; Dr Irene Koek, Chief, Infectious Diseases Division, USAID; Dr Mario Raviglione, WHO Director, Stop TB; and Ms Fernanda Teixeira, Secretary General of the Red Cross Society of Mozambique, IFRC.

    Looking forward, the African Union may officially endorse and support the TB emergency declaration during its upcoming meeting 10-14 October in Gaborone, Botswana. For more information click here.

  • 2005 UN World Summit report calls for strengthened commitments for TB control
    World Health Organization -- The 2005 World Summit in New York, marking the 60th anniversary of the United Nations, was the largest gatherings of Heads of State and Government in history. Including substantial emphasis on health and development, the World Summit Outcome document emphasizes:

    "Stressing the need to urgently address malaria and tuberculosis, in particular in the most affected countries, and welcoming the scaling up of all efforts in this regard of bilateral and multilateral initiatives."

    The document additionally includes several commitments to promote sustainable long-term funding for TB, strengthen public-private partnerships, develop new TB drugs, diagnostics and vaccines, and strengthen health systems in Africa.

    Read more ...

  • Upcoming meeting: 36th Union World Conference on Lung Health of the International Union against TB and Lung Disease (the Union) 18-22 October 2005 in Paris, France.
    The focus will be "Scaling up and sustaining effective tuberculosis, HIV and asthma prevention and control". The Stop TB Partnership and WHO have a number of activities and meetings planned. For more information on Partnership meetings, see relevant sections below. For more about the conference click here.

 

ADVOCACY, COMMUNICATIONS AND SOCIAL MOBILIZATION (ACS)

  • WHO and the Stop TB Partnership worked effectively together to generate enormous global and regional media coverage of the Africa TB emergency declaration in Maputo, including major news stories on BBC World Service Radio and TV, BBC domestic service, CNN International, more than 100 newspapers across Asia, Europe and North America, and intensive coverage in South Africa and other sub-Saharan African countries.

  • In a press event in Kiev the Ukrainian Minister of Health announced a new 3-year, $2.5 million grant of TB drugs to Ukraine by the Global Drug Facility (see below). The event generated broad coverage in the Ukrainian television, press and on-line media, and was a key opportunity to applaud and reinforce Ukraine's recent commitment to scale up DOTS services.

 

GLOBAL DRUG FACILITY

  • Results of the 12th Round of Applications to the GDF
    The 12th meeting of the GDF Technical Review Committee (TRC) was held on 15-18 August 2005 at WHO Headquarters in Geneva. The TRC is an independent body of international TB and drug management experts responsible for evaluating country applications to the GDF. The TRC considered applications from 10 different countries of which 6 were approved for new or continued support: Cameroon, Haiti, Rwanda, Sri Lanka, Togo and Ukraine. To date, the TRC has approved more than 80 applications to the GDF.

  • 36th IUATLD World Conference on Lung Health, 18-22 October
    Together with the NGO Management Sciences for Health (MSH), GDF is organizing a 1-day workshop during the IUATLD conference on "Strengthening Medicine Supply in National TB Programmes: Practical Guidelines and Tools", to be held on 19 October.

  • GDF drug management workshops
    In November 2005, GDF is hosting two drug management workshops for consultants. The first is for the South East Asia and Western Pacific regions to be held 7-11 November in Hanoi, Viet Nam, and the second is for Central Asian Republics to be held 14-18 November in Almaty, Kazakhstan.

  • GDF issues Expression of Interest
    The GDF is searching for qualified procurement agents to undertake the purchase of second-line anti-TB drugs from a selection of suppliers for delivery to a number of Green Light Committee (GLC) approved projects. The second-line anti-TB drugs will have a value of around US$ 5 million per annum. Click here for the official announcement.

  • Tender for new GDF Quality Control Agent
    The GDF will be conducting a tender opening session at the current procurement agent's (IAPSO) headquarters in Copenhagen for the selection and award of the new Quality Control Agent. More news on the outcome of this exercise will follow shortly.

  • GDF initiates process for ISO 9001: 2000 certification
    Currently, all internal quality maintenance procedures already in place within the GDF are laid down in the form of Standardized Operating Procedures (SOPs) and the relevant forms and documentation are developed. By the end of October the official ISO inspection will take place, and if all goes well the GDF will be ISO Certified by 10 November.

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TB AND POVERTY

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SECOND GLOBAL PLAN TO STOP TB (2006-2015)

  • Draft of the Global Plan to Stop TB (2006-2015) is now available for comments
    The Stop TB Partnership is developing the second Global Plan to Stop TB (2006-2015) as a successor to the first Global Plan (2000-2005). The Plan is still a working draft and your comments on it are welcome. Please send your comments to globalplantostoptb@who.int by 18 October. The Plan will then be finalized by end-October and launched at the World Economic Forum in Davos, Switzerland, on 29 January 2006.

    To view the draft plan, click here.

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NEWS FROM PATIENTS AND THE AFFECTED COMMUNITY

  • LHL and Stop TB Partnership appoint focal point for patients and affected communities
    Patient-centered approaches and the involvement of patients and affected communities are increasingly referenced in the professional TB community, but there are few initiatives that have explored or documented these resources comprehensively. The Norwegian Association of Heart and Lung Patients (LHL) has seconded Ted Torfoss to the Stop TB Partnership Secretariat as a focal point on this issue for an 11-month period. His role will be to coordinate activities with national and global networks of the affected community to empower, involve and mobilize patients and the affected community at different levels.

  • Participation in the 1st meeting of the Sub Group on Advocacy, Communications, and Social Mobilization at Country Level
    The TB-affected community has taken some important steps forward with the appointment of representatives to the Stop TB Coordinating Board and several of the Stop TB Working Groups. The latest development was participation in the first meeting of the Subgroup on Advocacy, Communications, and Social Mobilization at Country Level, held in Mexico City from 13-16 September, where patient and affected community involvement was made an important part of the new 10-year plan for ACSM at country level.

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WORKING GROUPS

Joint meeting

  • Joint meeting of the DOTS expansion, TB/HIV and DOTS-PLUS for MDR-TB working groups :
    15-17 October, Palais des Congrès, Versailles, France
    18 October, Palais des Congrès, Paris, France

  • Meeting of the subgroup on childhood TB: Monday afternoon, 17 October 2005, Palais des Congrès, Versailles, France.
    For more information, contact the chair of the subgroup, Professor Robert Gie at rpg1@sun.ac.za

Working Group on New TB Drugs

  • Upcoming events

    Annual Meeting of the Stop TB Partnership Working Group on New TB Drugs
    19 October 2005, 8:30 am - 12:30 pm
    Hotel Royal Monceau, Paris, France
    For more information email: stoptbdrugwg@tballiance.org

    Symposium on Recent Advances in TB Drug Development
    20 October 2005, 8:00 am - 10:15 am
    Palais des Congres, Paris, France

    Symposium on TB-HIV Co-treatment Issues
    21 October 2005, 14:00 pm - 16:15 pm
    Palais des Congrès, Paris, France

    View PDF flyer for the above events.

    Issues in TB Drug Development: Open Forum
    December 6-7, 2005, Washington, D.C.
    For more information email:
    TBDrugForum@courtesyassoc.com

  • European Parliament Adopts Resolution Supporting R&D for New TB Drugs

    On September 8, 2005 the European Parliament passed a resolution calling for commitment and funding for innovation to fight TB and other neglected diseases. The resolution identifies public-private partnerships such as the TB Alliance as "key to innovation and capacity building." For the full text of this resolution, please click here.

Working Group on Advocacy, Communications, and Social Mobilization

  • Past workshop: Introduction to Advocacy, Communication and Social Mobilization Workshop - International Training in Tuberculosis Control.

    Held at the Research Institute of Tuberculosis (RIT), Tokyo, Japan
    September 2005.

  • Meeting of the Sub Group on Advocacy, Communication and Social Mobilization at Country Level: 13-16 September 2005. Sponsored by the Mexican Ministry of Health, Mexico City, Mexico.

    For more information click here.

Working Group on New TB Diagnostics

  • Annual Meeting of the Stop TB Working Group on New Diagnostics: Thursday, 19 October, 12:30-16:30, Havane Amphitheatre, Palais de Congres, Paris.

    To view the agenda click here.

    For more information, contact Laurence Perret, Foundation for Innovative New Diagnostics at: laurence.perret@finddiagnostics.org.

Development of new TB tools

"Grand Challenges in Global Health", a Bill & Melinda Gates Foundation initiative, has awarded $45 million to support three major new projects on TB:

  • Biomarkers of Protective Immunity Against TB in the Context of HIV/AIDS in Africa, $13.1 million

    Stefan H.E. Kaufmann of the Max Planck Institute for Infection Biology in Germany will lead an international consortium in an attempt to identify immune system differences between people who are exposed to TB and never become sick, and those who develop serious disease. The researchers will focus particular attention on people infected with both TB and HIV.

  • Drugs for Treatment of Latent Tuberculosis Infection, $20 million

    Douglas Young of Imperial College in London will lead an international collaboration to fill a critical gap in currently available TB treatments: curing latent TB infection. Dr. Young's team will attempt to understand the fundamental biology of latency and use this to develop drugs that are effective against latent TB. Their work could also lead to improved treatments for active TB disease.

  • Preclinical and Clinical Evaluation of a Post-Exposure TB Vaccine, $11.3 million

    A team led by Peter Andersen of the Statens Serum Institute in Denmark will try to identify the mechanisms that allow TB bacteria to escape the natural immune responses that help some people keep the disease under control while others succumb to serious illness, particularly people with HIV. With this information the project hopes to design and test a therapeutic vaccine that can stimulate the immune systems of people with latent TB to eliminate the infection.

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RECENT MEETINGS

  • VI National TB Programme Manager's meeting of the Americas Region took place in Quito, Ecuador, 23-25 August 2005.

  • Following this meeting was the first meeting with the Regional Stop TB Partners took place on Friday 26 August 2005 to discuss the preparation of a future Stop TB Regional Partnership for the Americas.

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Hot Topics

36th Union World Conference on Lung Health

http://www.worldlunghealth.org

Stop TB Partnership Secretariat new staff

Rachel Bauquerez, Technical Officer, will work on developing an action plan by each of the three R&D Working Groups for drugs, diagnostics and vaccines.

Homero Hernandez, Technical Officer, is responsible for coordinating GDF application and review activities.

Luis Lourenco will be an intern with GDF for 3 months to work on expanding the current GDF catalogue to include paediatric anti-TB drug formulations.

Vacancies

TBP is looking for a Procurement Officer in charge of coordinating GDF activities in the Procurement and Supply Management (PSM) sub team. Vacancy now open (STB/05/TA336), if interested please apply at: The WHO vacancies page.

New Publications

For a list of WHO TB publications visit: The WHO 2005 publications page.

For a list of Stop TB Partnership Publications visit: The Stop TB Partnership documents page.

WHO Report: Task Analysis - The Basis for Development of Training in Management of Tuberculosis. 2005. WHO/HTM/TB/2005.354 Click here for the document.

Global TB Alliance for TB Drug Development Newsletter, September 2005. Click here for the newsletter.

WHO HTM Cluster Newsletter (HIV/AIDS, Tuberculosis and Malaria) Volume 4, September 2005. Click here for the newsletter.

Upcoming Events

Online Event Calendar

Meeting with G8 technical counterparts, 14 October, Versailles, France.
Organized by WHO and the Stop TB Partnership to discuss follow-up to the G8 Gleneagles declaration and implementation plans for G8 recommendations.

The 9th Stop TB Coordinating Board Meeting is to take place in Assisi, Italy, 10-11 November 2005.
For more information click here

New Partners

The following is a list of new Partners who have joined the Stop TB Partnership since the last Communiqué. To view the list click here.

To apply to become a partner visit: click here

This issue can be found online at /email/communique/communique_042.htm www.stoptb.org
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