Welcome to the website of the Global Laboratory Initiative (GLI)

The Global Laboratory Initiative (GLI) is a network of international partners dedicated to accelerating and expanding access to quality assured laboratory services in response to the diagnostic challenges of TB, notably HIV-associated and drug-resistant TB. The GLI provides a focus for TB within the framework of a multi-faceted yet integrated approach to laboratory capacity strengthening.

News

GLI core group collaborates with WHO on development of Framework of indicators and targets for laboratory strengthening under the End TB Strategy

18 October 2016- The End TB Strategy calls for the early diagnosis of TB including universal drug-susceptibility testing (DST), and a prerequisite for any national TB programme to reach this goal is a quality-assured laboratory network equipped with rapid diagnostics. The newly published WHO Framework of indicators and targets for laboratory strengthening under the End TB Strategy, developed in collaboration with a team from the GLI core group, serves as a guide for all countries developing plans for laboratory strengthening during 2016-2025.

The 12 core indicators under the Framework measure programmes’ capacity to detect TB accurately and rapidly using new diagnostics, provide universal DST, and ensure the quality of testing. These indicators will be monitored globally by WHO as countries progress towards reaching the targets. The Framework also provides methods for calculating country-specific targets for the numbers of tests and facilities needed for each of the main diagnostic technologies. Given advancements in diagnostic technologies and the need for country-specific targets that consider epidemiology and issues of patient access, the previous global targets that were based on numbers of facilities relative to the general population (1 microscopy center per 100,000 population, 1 culture facility per 5 million population, etc.) are no longer recommended.

The Framework is available online at www.who.int/tb/publications/labindicators

1st Global Laboratory Initiative for Africa (GLI Africa) Country Workshop held in Uganda

Over 100 participants gathered in Kampala, Uganda, for the 1st GLI Africa Country Workshop on Strengthening TB Diagnostic Networks in Africa. The three-day workshop (19-21 July 2016) brought together representatives of National TB Control Programmes and National TB Reference Laboratories from more than 20 African countries, technical partners, multilateral agencies, donors, and other key stakeholders.

The workshop identified key priorities for strengthening TB diagnostic networks in Africa, and included discussions on improving the interface between laboratories and clinicians, building country-specific specimen referral networks, implementing new WHO policies and GLI practical guidance and tools, establishing electronic data connectivity solutions, and coordinating technical assistance. Participants also drafted the Kampala Declaration, which describes the next steps needed to strengthen TB diagnostic networks on the continent and affirms the role of GLI Africa as a partnership that can drive these steps forward.

GLI Africa was established in 2014 to support countries in the African region to achieve quality-assured, accessible and sustainable TB laboratories services. GLI Africa drives the adaptation and dissemination of global WHO policies and GLI practical guidance and tools, by coordinating technical assistance and building regional capacity to support its TB diagnostic networks.

The current Chair of GLI Africa is Amy Piatek (USAID) and the Vice-Chair is Kekeletso Kao (FIND). Core group members include Heidi Albert (FIND South Africa), Heather Alexander (CDC, current GLI chair), Affolabi Dissou (candidate SRL Benin), Yala Djamel (SRL Algeria), Jean Iragena (WHO Regional Office for Africa), Nazir Ismail (SRL South Africa), Moses Joloba (SRL Uganda), Teferi Mekonen (ASLM), Philip Onyebujoh (WHO Regional Office for Africa) and Tom Shinnick (former GLI chair). The GLI Africa secretariat function is provided by Obert Kachuwaire (ASLM). This 1st GLI Africa Country Workshop on Strengthening TB Diagnostic Networks was made possible with funding from USAID and PEPFAR.

GLI core group elects three new members

The GLI core group is happy to announce the election of three new members for the 2016-2017 term: Dr Lucilaine Ferrazoli, Dr Nguyen Van Hung and Dr Elisa Tagliani. Dr Ferrazoli is a research scientist in the TB and Mycobacteriology Laboratory of the Adolfo Lutz Institute in Sao Paolo, Brazil. Dr Hung is the Head of Department at the National TB Reference Laboratory at the National Lung Hospital in Hanoi, Vietnam. Dr Tagliani is a research scientist at the Emerging Bacterial Pathogens Unit of the San Raffaele Scientific Institute in Milan, Italy (SRL Milan).

The core group would like to deeply thank the members that have completed their terms - Dr Maria Alice da Silva Telles, Dr Armand Van Deun, Dr Richard Lumb and Dr Paul Klatser - for their years of contributions to the group.

Dr Heather Alexander, elected as Chair of the Core Group of the Global Laboratory Initiative (GLI)

Dr Heather Alexander was elected as Chair of the Core Group of the Global Laboratory Initiative (GLI) by the Core Group members. Dr Alexander joined the U.S. Centers for Disease Control and Prevention in 2005 and is currently the CDC Division of Global HIV and Tuberculosis (DGHT) TB and Clinical Monitoring Team Lead, expanding her efforts in support of integrated, patient-centered diagnostic laboratory capacity building.

During her tenure as a microbiologist in the Division of TB Elimination, International Research and Programs Branch, Dr. Alexander worked with the Foundation for Innovative New Diagnostics (FIND) to manage collaborative multidrug-resistant TB diagnostic evaluations and implementation studies in several countries including the Russian Federation, Uzbekistan, Nepal, and the Philippines, contributed to the development of WHO TB diagnostic policies, and conducted applied TB research in collaboration with DTBE’s Laboratory Branch.

In 2010, Dr. Alexander joined the Division of Global HIV/AIDS (DGHA), International Laboratory Branch (ILB) as the Tuberculosis and Opportunistic Infections Unit Lead. In this capacity, she focused on improving access to and uptake of rapid and accurate TB/HIV laboratory diagnostic services in PEPFAR-supported countries through strategic planning; laboratory quality management systems strengthening; implementing and assessing the impact of new TB diagnostics; and improving linkages between diagnostic testing and TB and HIV treatment.

Dr. Alexander received a Ph.D. in Microbiology and Molecular Genetics from Emory University (Atlanta, USA) in 2004 and currently is completing a Master of Public Health in Epidemiology at the same institution. She has been an active member of the GLI Core Group since 2011.