Welcome to the website of the New Diagnostics Working Group
The New Diagnostics Working Group is one of the seven Working Groups of the Stop TB Partnership. It aims at supporting the Partnership in its goal of elimination of TB, in particular by promoting the development and evaluation of new diagnostic tools.
The New Diagnostics Working Group is a network of experts representing stakeholders from academia, government, industry, NGOs and the patient community.
NDWG Annual Meeting 2015
3 December 2015, 9:00 - 12:30
CTICC - International convention centre, Cape Town, South Africa
The Annual Meeting of the New Diagnostics Working Group was held on 3 December 2015 at the 46th Union World Conference in Cape Town. The meeting reviewed three main areas of activity in which the NDWG has engaged to advance TB diagnostics research and development. In the first session we examined the promises of next generation sequencing for detection of anti-microbial resistance and presented progress on the development of the ReSeqTB data sharing platform. Presentations in the second session discussed the new priorities for drug susceptibility testing in order to ensure the successful adoption of new TB drug regimens and highlighted the role of laboratory-based approaches. The third session focused on the development of tests for progression of latent TB to active disease, which are required to efficiently introduce targeted preventive therapy and support the goal of TB elimination. In particular, we reported on the outcomes of an expert meeting organized by the NDWG in collaboration with partners and shared the latest updates on the development of target product profiles and study protocols.
10 million lives saved and 45 million TB cases avoided with Stop TB Partnership 5-year investment plan
The Stop TB Partnership launches the new Global Plan to End TB 2016-2020 - The Paradigm Shift
The world is losing its battle with tuberculosis (TB), which is now the biggest infectious killer globally, causing 1.5 million deaths every year. Without a clear investment plan and a complete overhaul in how this disease is tackled, TB is unlikely to be eliminated until the end of the 22nd century, and the world will miss the recently announced Sustainable Development Goal to end TB by 2030.
This will require a US$ 56 billion investment package from 2016-20, which will see 29 million people with TB receive treatment; save more than 10 million lives and prevent 45 million people from getting ill with TB. This investment will offer a huge return for affected individuals, their families, and their communities, and one of the highest returns on investment of any health intervention - an estimated US$ 85 for each dollar invested. This is clearly outlined in the new Global Plan to End TB 2016 -2020 launched by Stop TB Partnership.
The battle with TB cannot be won without new tools. For this, as part of the total package, the Global Plan calls for a US $9 billion investment needed for vital research and development to create a vaccine that protects people of all ages against TB, highly sensitively rapid diagnostic tests that can be implemented at the point of care, and drug regimens (including for drug-resistant TB) that are highly effective and non-toxic. Read more...
Access to key documents
- Download the Global Plan to End TB 2016-2020 (full document)
- Executive summary
- Q&A on the Global Plan
International partnership to create global TB data sharing platform
The NDWG is partnering with CPTR, FIND and a consortium of other international stakeholders to develop a Rapid DST Data Sharing Platform. The initiative addresses the need for a centralized data resource for globally diverse genomic and other clinically relevant tuberculosis data. Data contributed from a variety of research, academic and government bodies will be reviewed for quality in a transparent manner, standardized, and eventually made accessible to TB researchers and clinicians. This collaborative effort will contribute to advance the understanding of genetic mutations and mechanisms associated with drug resistance, thus supporting the development of new diagnostic tests to detect drug-resistant TB. News release
NDWG activities in support of data sharing
Presentations and meeting reports are available here.