Welcome to the website of the New Diagnostics Working Group

The New Diagnostics Working Group is a one of the seven Working Groups of the Stop TB Partnership. It aims at supporting the Partnership in its goal of elimination of TB, in particular by promoting the development and evaluation of new diagnostic tools.

The New Diagnostics Working Group is a network of experts representing stakeholders from academia, government, industry, NGOs and the patient community.


Facilitating coordination of TB diagnostic research: NDWG workshop on sequencing data sharing

On 3-4 February 2014, the New Diagnostics Working Group held a workshop on "Enabling standards and sharing of data on the molecular basis of drug resistance" in London, UK. The event was jointly organized with the Critical Path to TB Drug Regimens (CPTR).The meeting aimed at establishing standards for the exchange of next generation sequencing data and for the combination with phenotypic DST results and clinical outcome. Participants also discussed possible mechanisms for sharing and making accessible this data to test developers, researchers, clinicians, and institutions performing diagnostics for treatment. This meeting is a successful example of how the NDWG provides a neutral coordination platform for multiple stakeholders in TB diagnostic R&D, thus playing a central convening role.

NDWG Co-Chairs, Dr Daniela Cirillo, San Raffaele Research Institute, and Dr Mark Perkins, FIND, chaired the meeting, which attracted 55 invited participants. These included experts from different backgrounds, such as TB sequencing groups, TB reference laboratories, TB clinicians, software developers, test developers, diagnostics industry, patent attorney, funding bodies, WHO, US CDC, ECDC, the European Commission, PHE and NGOs. The two-day workshop comprised of information sharing through presentations from attendees and circulation of published documents. The format of the event enabled focused debate in breakout groups and several plenary discussions aimed at consensus building.

The agenda and presentations are available under Meetings.

NDWG Annual Meeting 2013

Moving to point-of-care diagnosis (symposium and panel discussion)

31 October 2013, 9:00 - 12:30, Room Havane, Palais des Congrès, Paris, France

The New Diagnostics Working Group held its Annual Meeting 2013 in conjunction with the 44th Union World Conference on Thursday, 31 October 2013 in Paris, France.

In the meeting we reviewed scientific and technological advances that could foster the development of rapid point-of-care tests for TB.

Speakers highlighted the importance of global coordination for successful development of new TB diagnostics and discussed challenges for adoption and scale-up. Presenters also gave updates on progress made in biomarker discovery and whole genome sequencing, and introduced novel promising technologies. A panel discussion on priorities and approaches to address existing barriers to delivering point-of-care tests for TB closed the session.

Agenda | Presentations | Videos

NDWG to host a symposium at ESM Congress 2013

The Annual Congress of the European Society of Mycobacteriology will be held in Florence, Italy, from 30 June - 3 July 2013.

The NDWG will be hosting a symposium on Monday 1st July 2013 from 16:15 - 17:15. The session will focus on the role of next-generation sequencing for patient care and will include the following presentations:

  • Rapid whole genome sequencing as a tool to manage MDR/XDR-TB patients, Prof. Philip D Butcher, St George's University of London
  • Lessons on drug resistance from WGS of one thousand clinical isolates, Dr. Taane Clark, London School of Hygiene and Tropical Medicine
  • Low density microarrays as potential tools for DST in M. tuberculosis, Dr. Paolo Miotto, San Raffaele Scientific Institute

For more information on the congress, please visit www.esmcongress.org

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