On 1st July 2016, the NDWG convened an expert workshop on LTBI hosted by San Raffaele Scientific Institute in Milan, Italy. The objectives of the meeting were as follows:

  • To propose a standard terminology for LTBI and LTBI diagnostics.
  • To finalize the TPP for a test of progression and define a dissemination strategy for the document
  • To prepare an advanced draft of a guidance document for the evaluate of such a test and eventually submit it for WHO approval.
  • To provide an overview of the most promising research in this area.

Meeting Report

Executive Summary


List of Participants


Introduction and objectives of the meeting - Alberto Matteelli

LTBI conception: Definitions and relevance for diagnostic products - Frank Cobelens

Preliminary results of the online consultation on the draft TPP - Susanna Capone

TTP for a test of progression: Key areas to be addressed based on survey results - Samuel Schumacher

Framework for the evaluation of new LTBI tests - Sandra Kik

Genomic signatures - Thomas Scriba

Role of CD8 in progression from latent to active TB - David Lewinsohn