One of the best methods of laboratory strengthening is to implement a quality management system complying with the requirements of the international quality standard for medical laboratories, ISO 15189:2011. This website provides a stepwise plan to guide TB laboratories towards ISO 15189 accreditation. It was developed by the Royal Tropical Institute in cooperation with partners from the Centers for Disease Control and Prevention (CDC), The International Union Against TB and Lung Diseases and the KNCV Tuberculosis Foundation. The structure and contents of the tool are the result of two consensus meeting held at WHO headquarters in 2011.