Chairpersons: Daniela Cirillo, San Raffaele Scientific Institute, and Bill Rodriguez, FIND

Welcome and introduction
Daniela Cirillo

Part I - Use of next generation sequencing for detection of anti-microbial resistance

Scaling up sequencing in order to determine sequence diversity worldwide and for the identification of genetic variants that confer resistance to all old and new anti-mycobacterial drugs
Derrick Crook, University of Oxford

The ReSeqTB initiative and recent progress in the development of the data sharing platform
Angela Starks, CDC

User-friendly platforms for large data analysis
Stefan Niemann, Borstel Research Center

Session I audio

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Part II - New TB drug regimens and new priorities for DST

DST for Delamanid and quality control
Daniela Cirillo

Laboratory-based DST for Bedaquiline and introduction in countries
Leen Rigouts, Antwerp Institute of Tropical Medicine

Genetic diversity within MTB for the development of new DST
Claudio Köser, University of Cambridge

Session II audio

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Part III - Biomarker research and development of tests for progression of latent TB to active disease

Diagnostic markers for accurate prediction of activation of latent tuberculosis: Progress and needs
Mark Hatherill, University of Cape Town

Target Product Profile for a test for progression of latent tuberculosis infection
Claudia Denkinger, FIND

New predictive tests for the diagnosis of tuberculosis infection: How should they be evaluated and what evidence is needed for WHO endorsement
Frank Cobelens, KNCV and AIGHD

Session III audio

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