WHO Guidlines & Policy


  • Xpert MTB/RIF assay for the diagnosis of pulmonary and extrapulmonary TB in adults and children (2013) Updated policy statement
  • Using the Xpert MTB/RIF assay to detect pulmonary and extrapulmonary tuberculosis and rifampicin resistance in adults and children Expert Group meeting report
  • Automated real- time NAAT for Tuberculosis and Rifampicin Resistance (2011) Policy statement

Line Probe Assay (LPA)

  • Molecular Line Probe Assays for rapid screening of patients at risk of multidrug-resistant tuberculosis (first-line LPAs) (2008) Policy statement
  • The use of molecular line probe assay for the detection of resistance to second-line anti-tuberculosis drugs Expert Group meeting report

Culture and drug susceptibility testing (DST)


  • Fluorescent light-emitting diode (LED) microscopy for diagnosis of tuberculosis (2010) Policy statement
  • Same-day diagnosis of tuberculosis by microscopy (2010) Policy statement
  • Approaches to improve smear microscopy for TB diagnosis Expert Group meeting report
  • Definition of a new sputum smear-positive TB case (2007) Policy
  • Reduction of number of smears for the diagnosis of TB Policy

Interferon-gamma release assays (IGRAs)

Commercial serodiagnostic tests